{"id":18917,"date":"2024-03-19T07:00:00","date_gmt":"2024-03-19T11:00:00","guid":{"rendered":"https:\/\/foodmedcenter.org\/?p=18917"},"modified":"2024-03-16T18:45:59","modified_gmt":"2024-03-16T22:45:59","slug":"diet-genes-and-choices-study-spotlight-takeaway-with-chef-dr-mike","status":"publish","type":"post","link":"https:\/\/foodmedcenter.org\/zh_cn\/diet-genes-and-choices-study-spotlight-takeaway-with-chef-dr-mike\/","title":{"rendered":"Diet, Genes, and Choices Study Spotlight Take-Away with Chef Dr. Mike"},"content":{"rendered":"\n

\u201cEveryone goes through a period of Traviamento – when we take, say, a different turn in life, the other via. Dante himself did. Some recover, some pretend to recover, some never come back, some chicken out before even starting, and some, for fear of taking any turns, find themselves leading the wrong life all life long.\u201d<\/em>
\u2015 Andr\u00e9 Aciman, Call Me by Your Name<\/em><\/p>\n\n\n\n

The presence of a link between what we eat and what we are is nothing new. Brillat-Savarin succinctly summed that up almost 200 years ago in 1825 when he wrote, \u201cTell me what you eat, and I will tell you who you are.<\/em>\u201d What we choose is what we manifest.<\/p>\n\n\n\n

What is new is the ability to identify how what we eat can influence specific genes to turn on or off. The mere presence of certain genes does not necessarily condemn us to a preordained fate. A critical step is the process of flipping the switch to either turn a particular gene on or off, the result of which produces various molecular phenotypes.<\/p>\n\n\n\n

A molecular phenotype refers to \u201cthe observable characteristics or traits of an organism that result from the interaction of its genes (genotype) with the environment at the molecular level.<\/p>\n\n\n\n

By studying molecular phenotypes, researchers can gain insights into how genes are expressed and how they function in different biological processes.\u201d<\/p>\n\n\n\n

One way to investigate is to look for gene expression quantitative trait loci (eQTLs), which are regions in our DNA that are associated with the expression levels of genes. In other words, not the regions of the DNA that contain genes (coding regions), but the non-coding regions (for years thought to be extraneous, wasted bits of DNA code) that influence the expression of genes. One way to imagine their function is to view them as a volume knob \u2013 they don\u2019t choose what song is being played, but they help determine whether you actually hear it or not.<\/p>\n\n\n\n

In this week\u2019s study, researchers used eQTLs to gain insights into the molecular mechanisms underlying the connection between what we eat and the genes that are turned on or off \u2013 a process that has vast implications with respect to chronic disabilities and diseases, as well as health and wellness. Understanding these relationships and being able to identify them is a key step in developing personalized treatment strategies and diets based on an individual’s genetic profile and gene expression patterns.<\/p>\n\n\n\n

The Study:<\/a><\/p>\n\n\n\n